Blah, blah, blah.
The grip safety is a problem, if you ever fail to naturally and reliably depress it sufficiently to permit firing when the trigger is pressed, on your CCW or home defense gun, including with grabbing the gun in a "panic grip" or other less-than-perfect grip.
The GS is a feature which potentially interferes with the function of a piece of lifesaving equipment, especially so for those who carry in Condition One, and who therefore must depress the thumb safety before trigger operation is possible, and who leave the thumb on top of the safety lever after depressing it.
The alternatives are to:
1. pin the grip safety,
2. get the Novak modification which creates a unitary backstrap (does away with the grip safety and its function altogether),
3.) build a great big hump onto the GS so that the palm of the hand always depresses it,
4.) shoot with a "thumb below the safety" grip, which requires repositioning of the thumb after depressing the thumb safety and therefore unavoidably slows pistol operation,
5.) stop using a 1911 for defense, and get some different sort of gun which has no GS issues, and
6.) carry in Condition Two or Condition Three, with the attendant complications & problems associated with those carry modes.
I believe most here would be unhappy with choices 4, 5 and 6. I personally choose option 3. I wouldn't mind trying option 2, but it's too expensive.
The real issue here is NOT one of safety, but of the likelihood that an unscrupulous attorney, manipulating an ignorant and uneducable jury, would paint you, who would in truth be the righteous defender of self or family, as a wanton, careless, even bloodthirsty person for sake of having "deactivated a safety device" on a gun used in a shooting. (It goes without saying that part of said attorney's case would be the allegation that you fired in error because of the GS having been deactivated, even if that were blatantly and obviously untrue, and you fired willfully and purposefully in order to defend life and health.)
We all know this to be nonsense, and apart from the Springfield Armory XD derivative and its parent gun, the Croation HS2000, there aren't any currently produced handguns other than the 1911 which even employ a GS so far as I know (and the GS on the plastic pistols basically can't fail to be depressed with a shooting grip IME ), so it can't be a necessary part on modern handguns.
Having to worry about it is a lawyer-created problem!